[3] The bumps may become small blistersor plaques and may appear bloody,[3]often healing with minimal scarring. Gruber-Wackernagel A, et al. More people experience polymorphic light eruption at high altitude than at sea level.[1]. This is a type of distinct, circular bump that occurs due to, Erythema multiforme causes a distinctive rash resembling a bull's-eye. Polymorphous light eruption, also known as "sun allergy" or "sun poisoning" is the most common photosensitivity. Presents predominately between 2040 years of age. Suitable investigations to determine the exclusion of cutaneous lupus erythematosus include full blood count; circulating antinuclear antibodies (ANA); extractable nuclear antigens (ENA); and direct immunofluorescence on histopathology. Photosensitivity. MNT is the registered trade mark of Healthline Media. The eruption appears first on limited areas, but becomes more extensive during subsequent summers. Well go over the causes of an ear keloid before diving into. It occurs 1-2 days after intense sun exposure. 2008 May;58(5 Suppl 2):S149-54. The reaction usually happens during spring and early summer when exposure to sunlight increases. In: Nelson Textbook of Pediatrics. The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). McKee PH, J. Calonje JE, Granter SR. Sunscreens. Unable to load your collection due to an error, Unable to load your delegates due to an error. An itchy rash will appear on areas that were newly exposed to the light, including: The rash usually doesnt affect the face. Frequency of occurrence of polymorphic light eruption in patients treated with photohardening and patients treated with phototherapy for other diseases. You're likely to start by seeing your primary care doctor. When the oedema is massive the lesions may resemble erythema multiforme clinically. Some people are able to build a tolerance to UV light by gradually spending time outdoors or using phototherapy. Polymorphic light eruption (PLE) is the most common photodermatosis, with a prevalence of 10-20% in the North American and European population ( 1,2 ). There are many clothing choices that can help you do this, such as: Polymorphous light eruption is a condition that causes your skin to react to light, usually UV light. However, it may be genetic. Dermatologists can expose you to UV light a few times per week before the sun becomes strong in the spring to help avoid severe PMLE. Polymorphic light eruption (PMLE) is a form of photosensitivity, which usually occurs in younger females.It is more common in patients who receive only intermittent sun exposure and typically consists of crops of papules, vesicles or plaques.. Histology of polymorphic light eruption. PMLE is generally treatable with both home remedies and medical interventions. Topics AZ DermNet does not provide an online consultation service. Patients with PMLE can develop a tolerance during summer months. Our expert physicians and surgeons provide a full range of dermatologic, reconstructive and aesthetic treatments options at Cleveland Clinic. 2023 Healthline Media UK Ltd, Brighton, UK. The British journal of dermatology. Seborrheic dermatitis commonly affects the skin on the chest, causing a red, scaly rash to appear. [2] However, the "hardening" effect, with respite during the later summer, frequently occurs with gradual exposure of sunlight,[5] eventually leading to significant improvement. Accessed Dec. 9, 2021. This site needs JavaScript to work properly. PMLE is characterized by recurrent, abnormal, delayed reactions to sunlight, ranging from erythematous papules, papulovesicles, and plaques to erythema multiforme -like lesions on sunlight-exposed surfaces. It is postulated that there is a delayed hypersensitivity reaction to an endogenous antigen expressed after exposure to sunlight or artificial sources of ultraviolet (UV) radiation. You can learn more about how we ensure our content is accurate and current by reading our. Ultraviolet-radiation-induced erythema and suppression of contact hypersensitivity responses in patients with polymorphic light eruption. As the name suggests, clinical features can vary poly meaning many, morphic meaning forms. 1 mo. Photodermatol Photoimmunol Photomed. Polymorphic light eruption occurs in 18% of Europeans and does not show higher prevalence with increasing latitude: multicenter survey of 6,895 individuals residing from the Mediterranean to Scandinavia. The eruption can appear within hours of sun exposure and last for days. [4], Typically, the first episode develops in the spring following the first exposure to intense sun. Gruber-Wackernagel A, et al. This typically has to be repeated after every winter. However, positive antinuclear antibody and extractable nuclear antigen (anti-Ro/La) in low titer may be detected, even in the absence of other criteria to suggest a diagnosis of lupus erythematosus. //]]>. The rash usually appears as tiny, inflamed bumps or slightly raised patches of skin. Eye. Read on to learn more about PLE, including the symptoms, causes, and treatments. Schweintzger N, Gruber-Wackernagel A, Reginato E, Bambach I, Quehenberger F, Byrne SN, Wolf P. Br J Dermatol. Dec. 16, 2021. If your symptoms are severe, your health care provider may prescribe anti-itch medicine (a corticosteroid cream or pill). Gradual hardening is one form of treating PMLE. The exact cause of PMLE isnt known, but genetics are thought to play a role. Duration: can last from days to weeks and resolves faster if further sun exposure is avoided. Some people with PLE may find they react to even small exposures to sunlight, while others develop PLE only after a certain amount of time in the sun or as a result of repeated exposures. 60% of patients yielding a positive eruption are clinically and. While the rash varies from person to person, the particular rash you get will typically be similar every time it happens. This won't totally protect you from a reaction, as ultraviolet A may penetrate through most sunscreens. PMLE can be seen in all races and all skin types. These healthcare professionals should educate the patients on preventio which includes wearing appropriate garments when going outside and use ample sunscreen frequently. Hlzle E, Plewig G, von Kries R, Lehmann P. J Invest Dermatol. It is most often found in females in the second or third decade of life and occurs in 10-15% of the U.S. population. About three-quarters of patients acquire PLE after UV-A exposure only, one-tenth after UV-B exposure only, and the rest after a combination of UV-A and UV-B exposure. doi: 10.1111/1523-1747.ep12468916. Bookshelf Women and people assigned female at birth. PLE is a skin rash that occurs in response to sunlight. You can learn more about how we ensure our content is accurate and current by reading our. The hardening effect, where further exposure to UV prevents the eruption, is not fully understoodand could involve tanning, hyperkeratosis, and acanthosis of the epidermis, and/or the development of immunological tolerance. The patient is exposed ideally to UVA (alternatively UVB) daily for 35 days to a small area of skin (such as the forearms or v of neck), which elicits an eruption. Follow care instructions on the label of UV-blocking clothes to maintain their protective feature. Dermatology Made Easybook. Ultraviolet radiation causes less immunosuppression in patients with polymorphic light eruption than in controls. In the northern hemisphere, people who are prone to PLE often experience this condition in spring, when light levels begin to increase and people start wearing clothes for warmer weather. Polymorphic light eruption (PMLE) is a seasonal, acquired, idiopathic photodermatosisoccurring in spring and early summer. Dark lips are often the result of hyperpigmentation. Exp Dermatol. Polymorphic light eruption, Author(s): Dr Prudence Gramp, Dermatology Department, Gold Coast University Hospital, Australia. The rash most commonly appears on your: Juvenile spring eruption is a type of PMLE that tends to affect the ears of children (mostly boys). PLE is considered as a delayed hypersensitivity response to newly UV induced, but still unidentified, antigen(s). Accessed Dec. 9, 2021. Describe the pathophysiology of polymorphic light eruption. 2008 Aug; [PubMed PMID: 18510674], Papular polymorphic light eruption on lower legs in female. A rash can be a symptom of many different conditions. Whether administration of estrogen in the form of oral contraceptives or postmenopausal replacement therapy might induce high ANA levels in a healthy individual cannot be ascertained from our data. Elsevier; 2020. https://www.clinicalkey.com. Do you have any brochures or other printed material I can take with me? [2], The photosensitivity connected with lupus erythematosus is the main condition that may appear like PLE. Erythema multiforme, Pathology of the Skin (Fourth edition, 2012). There is a genetic susceptibility in 1546% of cases where a positive family history is reported. [22], Generally, PLE resolves without treatment; also, PLE irritations generally leave no scar. Phototherapy Idiopathic photodermatosis; Immunomediated photodermatosis; Minimal erythema dose; Photoprovocation tests; Phototests; Polymorphous light eruption; UV light. The cause of polymorphic light eruption is unknown. A mucin stain will be negative and confirm dermal oedema rather than mucin (which would suggest a form of lupus). FOIA It is possible that people with PLE have some resistance to this UV-induced immunosuppression, which could result in skin inflammation, a 2022 review of research suggests. Phototesting is rarely necessary. If the symptoms do not improve or are severe, a doctor may prescribe: Because people get vitamin D from the sun, people with PLE can be more at risk for vitamin D deficiency. 2004 Feb;122(2):291-4. doi: 10.1046/j.0022-202X.2004.22213.x. 9500 Euclid Avenue, Cleveland, Ohio 44195 |, Important Updates + Notice of Vendor Data Event, (https://www.aocd.org/page/PolymorphousLightE), (https://www.cdc.gov/nceh/features/uv-radiation-safety/index.html), (https://dermnetnz.org/topics/polymorphic-light-eruption), (https://www.nhs.uk/conditions/polymorphic-light-eruption/), (https://www.ncbi.nlm.nih.gov/books/NBK430886/). Polymorphic Light Eruption (PLE) (also known as polymorphous light eruption and benign summer light eruption) is a recurrent, itchy skin eruption occurring on exposed skin sites after sun exposure, which heals without scarring within 14 days ().The presenting skin eruption is most commonly spots and blisters but may also take other forms, including plaques (raised . Patterson JW. Note that this may not provide an exact translation in all languages, Home Low-dose narrowband UV-B and other forms of phototherapy undertaken in late winter or early skin can reduce the incidence and severity of polymorphous light eruption. It occurs after solar or artificial UV-light exposure and affects only the sun-exposed areas with preference of the V-area of the chest, of arms and forearms, legs, upper part of the back, and rarely the face. Polymorphous light eruption (PMLE) is an acquired disease and is the most common of the idiopathic photodermatoses. We avoid using tertiary references. Any medical information published on this website is not intended as a substitute for informed medical advice and you should not take any action before consulting with a healthcare professional. Therapy is based mainly on topical or systemic corticosteroids. It is more common in people with lighter skin. https://www.merckmanuals.com/professional/dermatologic-disorders/reactions-to-sunlight/photosensitivity?query=photosensitivity#. The best way to address PMLE is to avoid direct sun during the strongest parts of the day, wear appropriate sunscreen, and wear clothing that covers your skin. 2023 Healthline Media LLC. Figure 1 In: Weedon's Skin Pathology. Polymorphous light eruption (PMLE) is a common skin rash that develops in people who are sensitive to ultraviolet (UV) light. Mayo Clinic College of Medicine and Science, Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Graduate Medical Education, Mayo Clinic School of Continuous Professional Development, Mayo Clinic on Incontinence - Mayo Clinic Press, NEW Mayo Clinic on High Blood Pressure - Mayo Clinic Press, Mayo Clinic on Hearing and Balance - Mayo Clinic Press, FREE Mayo Clinic Diet Assessment - Mayo Clinic Press, Mayo Clinic Health Letter - FREE book - Mayo Clinic Press, Financial Assistance Documents Minnesota, Book: Mayo Clinic Family Health Book, 5th Edition, Newsletter: Mayo Clinic Health Letter Digital Edition. Elmets CA. Polymorphous light eruption: clinic aspects and pathogenesis. This rash is also known as PMLE, sun allergy or sun poisoning. Check out these best-sellers and special offers on books and newsletters from Mayo Clinic Press. Polymorphous light eruption(PLE) presents with itchyredsmall bumpson sun-exposed skin, particularly face, neck, forearms and legs. It is common among young women who live in moderate (temperate) climates. PLE commonly affects people for many years, but most peoples symptoms improve or disappear over time. What to wear to protect your skin from the sun. If you avoid UV light, your rash will heal on its own in a few days to weeks. DermNet does not provide an online consultation service. Boonstra HE, van Weelden H, Toonstra J, van Vloten WA. It is generally itchy and uncomfortable. Merck Manual Professional Version. PMLE typically resolves on its own without treatment. It also occurs more frequently in places that are at higher altitudes and in more temperate climates. The papular type is the most common. J Invest Dermatol. Epub 2014 Mar 27. If you have any concerns with your skin or its treatment, see a dermatologist for advice. Polymorphous light eruption (PMLE) is a common skin rash that develops in people who are sensitive to ultraviolet (UV) light. [5][6] It is also particularly more prevalent in Central Europe and Scandinavia. [5] In addition, it may occur in other parts of the body in some people treated for inflammatory skin diseases with phototherapy. UVA causes up to 9 in 10 cases of polymorphous light eruption. Lesions usually heal without scarring. There is someevidence to support prophylactic short courses of oral steroids (for example, to prevent the eruption during a holiday break), hydroxychloroquine, and antioxidants such as Polypodium leucotomes extract, lycopene, beta-carotene, nicotinamide and astaxanthin. American Academy of Dermatology. Melanoma prevention. Accessibility Photodermatol. Polymorphic light eruption codes and concepts, 238525001, 79372000, 238525001, 6618004, 54116000, 84036008, 51048002. Solar urticaria occurs during or shortly after exposure and resolves within an hour or soof covering up. Skin lesions typically appear within hours of sun exposure, but they sometimes occur days later. Note that this may not provide an exact translation in all languages, Home Epub 2017 Jul 17. What's the most likely cause of my symptoms? [4][8], PLE is also defined as an idiopathic primary photodermatosis,[9] in which the photosensitizer is unknown. J Am Acad Dermatol. Cream! Skin diseases due to physical and chemical causes", https://en.wikipedia.org/w/index.php?title=Polymorphous_light_eruption&oldid=1127125983, Skin conditions resulting from physical factors, Pages containing links to subscription-only content, Creative Commons Attribution-ShareAlike License 3.0, Shortly after sun exposure in people younger than age 30-years, This page was last edited on 13 December 2022, at 01:14.
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